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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44cf2fe6d703e81d88ad0771281061eea859f6b523c8bd9c4b83cd9c3afc7ff4' 
  AND token = 'zy8WJRt05AKEIP1A52/6MTOp0WdWEXfJnBpQP/flTCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}