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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '649ca352083fd526004c6bcc909bbebd59675a8e47ff6d8db433cb0f615b5821' 
  AND token = 'IsqSfeVtR01g0pTX7H9ZDjOUVZd5u4Wavs+y/zr+Wo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}