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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68afaee75a4288b22854ca57dd1a6de6d54d8f19d3269aab82b8acea8ff00de4' 
  AND token = '7cg6WK0RiSP3H+NGLDuR/mbXYcJMNL9eZ2+dWm3IxiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}