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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07739c5802d0dbd5d0aa4861b20531d5de495934bff6c44271eb15a31a440c8f' 
  AND token = 'DucdmmuT53KPpMdQcJgr2uxky5jouClF6F8acuCbN5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}