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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0674500cc4eaea095d74e676c3b6e97fe8d3ce380efcb0a0d856fc886ba77770' 
  AND token = 'A5G7mKJ0WkkuSlj2+nuWugS3I69aM3aVyxAgaqjcXnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}