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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab5324f84f8898f55fe480dc8fc93f9a72c1c3b9d6331e14d67fadf395a09f0' 
  AND token = 'f000pOwdR0J/hi614RRpJfTiSob9UUgDfirn22A33jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}