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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12618e890322224883c6a992d25fa2757c2251a5f9611521aa7a2facdc5a042a' 
  AND token = '5yFdrwSUxiBl6UfWVTcbfbIoD7vLhweK/lMp1bHKwV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}