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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f78ff051f13a67fbaf9a7839339a0a6b85745e6f5b47948df8198d31bc8d7b' 
  AND token = 'RWsUtch1MoSbXG4OdYH82lVGOGzt4rR9bcBOkDBgIIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}