SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5018d0aeef928b245b9df4b9b908e3d86d3afcb6594e5a22651e10cc37c9d39' 
  AND token = 'McoRTJTMFndbN8ezZ50Z1Wc7wnyWWKqaD87Am99TvrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}