SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a2a53ee39f3325aa34d892f5f687d62ed382d37283ab2fd990ea08e5dfa2e54' 
  AND token = 'i4O5EIj2kI3DvjhkUZ18B1aIjABKpbUmoh9d6pYJHpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}