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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa39064dc7fb8b10f646a4889d2fa96267569b703da39c85ab90a78d7d9425cf' 
  AND token = 'Twp5vhveVGlO7oA1h2gMQ03tRXh8t7vsrY9tcS0ubIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}