SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7953523e76d4972e28ac02704bf388c73ecbf9f7e035681ced54b3f53fcdc811' 
  AND token = 'd9XH53h6kF5pl4435Li8piwqi+rXLuAUMRsGsTEvqpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}