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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25c6ddf21fa8e751be11d454f3c2823f1fc802a38758ad58b250295a0db8748' 
  AND token = '8xA/70rpEcE+B0Xv8YTGz1+nyDZAGUGY8tTc0rrcAHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}