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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd05202f6dae62552170f01466ce8626e85c635fe7599c6e7eb0bc64a4b40c2a0' 
  AND token = 'IaixMwTkRk2AMo2Wr9zavEO/IEkQOXXIGWt6OS/O00E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}