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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1439e8c615a71322b85b1c9ca52a89399a46e9fa2f2d1e489fb2038b16841f5' 
  AND token = 'MPQXYRlQYJOGWPyDhDLxPlANdf4ZS09SM/UPZ7FKbNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}