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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7700f022e5b2e662e3467d2bdd80c699f4568c9ae4b9db6300d9aaa0d3fae342' 
  AND token = 'Tay8pNtMQT8zKAiLA9zHNL6Qal+WiWpOHkSWUYfFivM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}