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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3617a94f5d70ff90da7cae3fd86ae6fb5d23036a6989ebd30ac0c27ff3069abe' 
  AND token = 'GNa2sEkFurHZOS8VqxBx2dvRsmEA2UG26LHtx6IXFHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}