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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d4be5494e95b11aa070c36b47f379a54df95b277f5cff6e9bd5ec7f090f15c' 
  AND token = 'EyejUXN/601Oy6MRSm1XG/gOh0B6JegmLiiC4fCIYMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}