SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f45f439baca40b938a2a38a52ebe5f6c20f4afac7ed6d35d3aac455a9d6b3f' 
  AND token = 'ri8BvR8YNDq51iiUmFn3P7wvMH+Nwg2lX/MzZ+ec3jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}