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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b48aad445b72efbc7f80b18030c2305613218ccd8c0a2c1cc249752b782655c' 
  AND token = 'S4M0SwsZDpteAODigA9RdEZ5gUA/5/70Ct0SmWOW+2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}