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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4877df7de1c69782640c40464d43b1f40cd23a4bd1f03d8dee493adf705ff80f' 
  AND token = 'lWtF9VBAPe4V9r1U7v5SGFRkbEbNqYloKUfpFCMJAkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}