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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9413af278002e47d3585070093bbfb71d47f59864b1187fc9d403a48045918fd' 
  AND token = 'JKNP2i/c0iBOyflLTPCT45DA0IPRFPf3ZOz+Voh+EFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}