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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b856b49fb15620e2630521f32e6208379080f74e704a62657afc521e4157f625' 
  AND token = '37UCE+Wnj5ruGHgoZmctZNyCYL/iOWDmfoEPE4xjhq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}