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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f604d3f336f90e4947abdee21810cb464206a22e295154fe0e12141d3fb02d' 
  AND token = '7UXNP/1sxwtP06nkxoMDm2u240tfNef6TMxmQpZwgQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}