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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acb69f7eae599a9a2730af706809b25701a49581de1bb0c376f2b713dde97a8f' 
  AND token = 'OESdDlA9Q+MrgAg22+zthDMP7oJln4oo1GUKbnesdpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}