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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b8b3599b0d8d475162a4655e0049466d67c6cb26597ffa37fe6860d974cd1f' 
  AND token = 'SduU/XQcUBbD1hIDBLT0GC6R6fw7v3KEADquNMSQv6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}