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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35b64e36484d5a1e3721ad4c466b71e96b43dd10b982297f3f889dba472a4745' 
  AND token = 'IIuJujVF9N36Ygfz6uOrto/RtdAizen7CV9Xqv7aYD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}