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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a12978f7efc94df01d37959300a36d6048476a91a6ad3132bdab078a31b1a81b' 
  AND token = 'DR3PyLerdC9W7Z5MnQ27V0rMCmxM4OCyr9pYueOhqcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}