SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ffeb19be78349e82437aabcc6baf7b71b2a66be3c1b026d1971dad96629767d' 
  AND token = '4SJ9zSreRA9BHQWvwgk/nLNAbkryjyMF5R2Bp3FseI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}