SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f0aacb6ce44853208e8df0136408cdc4a6e86f22f4c799123eca309efbaf95' 
  AND token = 'CfnpGsyDuXBEiE4F/JMoENqYYlKIzb0h7DcNh6n3/PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}