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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c5800411e596cf3b3605ad6429346af0fb44d4fae7bcfb3ae8687ac383ef0bc' 
  AND token = 'TK0JYYKQSdN1v/el0djxW7m1idM8qMy0KSEy5EiEtxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}