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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27325105b6816d458c66f789bba501377afc69dd7ad0939af168ff4e5b7205c0' 
  AND token = 'UE5atsxU8UU2vfVFtXFpguCxOolvO5a/4NuIZavNQo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}