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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '442261d72842b165a7b255b7125bd258d6d885c14105352ba64ad71a5291d882' 
  AND token = '7QQ4+LXMS+XBRpqrJv6QroM4cZLzVj7TgiXnxxsnYPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}