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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b6d0bcf8a13b47e8ebd9b36c8aea331cc5641204c62b27c3659fe189e9b0e1a' 
  AND token = 'CTgE9KHNCW+VjkESK6UdhQZsADByHZjr1ZBWCKV4H2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}