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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01fbe181f43231fd6b59ff09346e1a150863d4a4fa092b9298e73d049dd13b3f' 
  AND token = '+WeA68M+vnmw+wdIvsRXseBKmPpM44CqSB1dP7wi2nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}