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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6227a92251a77f78886cd7697399583f8187bdafb8b547fc225f2f08e4ac5394' 
  AND token = 'FAWa59zDqSW09cuxl5lWiMLKJuvmHR/LIHqU0FnT/Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}