SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7235b7e7d7d1d21cab07b22cfae543d66e530f970b2680e5d698ee4eab5e6644' 
  AND token = 'njvnH0klFKrw8SVrnFtvl4jq/PX7KTV4CnDdeQ00W10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}