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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8b6a10913a8506564c1e2d9c673790021643915cf34cf99b0bab53f74e2ee9f' 
  AND token = 'iXWFz94LIdmJJn80L574WdoKWOZ8bYb4VlPJgmV0ctw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}