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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a895dc1c372e612c3f9fc024c982d29bbb270017ebf56a7a530495d3c08aa51' 
  AND token = '4FxVI2+QBEwcJ2kVTFYBrfB5+8PMRq+MB69Tc6eZQLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}