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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1426a620dc737413c9c8600c4d3a289023a4c2264fcde008403be4b6d9df5d2d' 
  AND token = 'UpO7FN89liC1E17ru76cDeosFA4qJ8FcCX8wdUTa3bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}