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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0fd2aa99dbc1ca1bab26ac84a23d29d6501da4250b20446fb6e1c3964c6c64' 
  AND token = '4yj7ob6VTjuLNNXV28F8Z0VIRbfy2DaXeLh5vWNG8uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}