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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd783b49afbc9d5fa22142f3a695e8415af0e5ed4b3db7477380b1aa5cbdcf12f' 
  AND token = 'HoY1ATDFEKbwUzFvidVeP4zDzIFDrQME6Q7mBxpMKhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}