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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5659e62efe8bfce9ff19040f58659e9b18dc31eb657c6f65aab79f020161ca98' 
  AND token = 'wr5Mn10ClZnQUnKonbT3CjmbjyqTMtCZtysprC9MBhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}