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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '582c2ded7a45ca3bc57b22154b5439cd796ab4eeb1c245a43d55f42d489e3e11' 
  AND token = 'qQ2e0GQpWAL93t0e0C1ajMdwz2mJEu+DzEawGTFKg7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}