SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1801fc72be73ab2a02078c6dd9c002ccdd6f3b7659f540ef5f8e3dba2b926a28' 
  AND token = 'y9P4dvI7vrN2XhEIvhyAFzEeWKCxLOLG9+LL2XVN+B0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}