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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad0f3294777dc49b82fb85b010bc6e73fb84313b5f952039db7d6378e5159f16' 
  AND token = '20w7X0XQPx3YA36dwdOKV8VvjTnW6KUTLRj2Lpw8gcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}