SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b49ea2ca1beea024526189e0abf67d516cd8a54238252119dd5b5266d2d12e1' 
  AND token = 'pv0cK78sMqSjI0uGK1iNp2zID55Rzic980nFbIGxPrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}