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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219659f76cc22b003d316f83c5d42b5351915d569a45da01f74de7d7d926fcc6' 
  AND token = 'L7z+nzzJ5QP3a4rUEpY5V4X94p7+o9YEC4AH33HskxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}