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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757e228fb67020a4108e8f23a1f4b30b30ed6761ffbed5e8cd1b2a084a471634' 
  AND token = 'X1kW8bV/QB94mFBb2InRvHT9ysA2JL0qnOvl7qJHq5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}