SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4735cafe7a339e369f3e1219aa7df9df25114c5ef2a6a9ee8d851fc6093e49' 
  AND token = '32cr1wq+pvWOC8pWQr5aw1LckHcIbG/Hjo3+jeyV6IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}